South Manchester
Functional Bowel Service

Severity in irritable bowel syndrome: a Rome Foundation Working Team report.

Drossman DA, Chang L, Bellamy N, Gallo-Torres HE, Lembo A, Mearin F, Norton NJ, Whorwell PJ.

Am J Gastroenterol. 2011 Oct;106(10):1749-59.

Abdominal Bloating and Distension: What Is the Role of the Microbiota.

Issa B, Wafaei NA, Whorwell PJ.

Dig Dis Sci. 2011 Jul 29. [Epub ahead of print]

Treatment of bloating and distension - role of probiotics.

Agrawal A, Whorwell PJ.

Aliment Pharmacol Ther. 2011 Sep;34(5):580-1; author reply 581-3.

Visceral hypersensitivity in endometriosis: a new target for treatment?

Issa B, Onon TS, Agrawal A, Shekhar C, Morris J, Hamdy S, Whorwell PJ.

Gut. 2011 Aug 25. [Epub ahead of print]

Collaboration with industry facilitates useful research that wouldn't happen otherwise.

Whorwell PJ.

Therap Adv Gastroenterol. 2011 Nov;4(6):343-63.

The LUCK study: Laxative Usage in patients with GP-diagnosed Constipation in the UK, within the general population and in pregnancy. An epidemiological study using the General Practice Research Database (GPRD).

Shafe AC, Lee S, Dalrymple JS, Whorwell PJ.

Therap Adv Gastroenterol. 2011 Nov;4(6):343-63.

Mood color choice helps to predict response to hypnotherapy in patients with irritable bowel syndrome.

Carruthers HR, Morris J, Tarrier N, Whorwell PJ.

BMC Complement Altern Med.

5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene and irritable bowel syndrome: effect of bowel habit and sex.

Niesler B, Kapeller J, Fell C, Atkinson W, Möller D, Fischer C, Whorwell P, Houghton LA.

Eur J Gastroenterol Hepatol.

The Patient Health Questionnaire 12 Somatic Symptom scale as a predictor of symptom severity and consulting behaviour in patients with irritable bowel syndrome and symptomatic diverticular disease.

Spiller RC, Humes DJ, Campbell E, Hastings M, Neal KR, Dukes GE, Whorwell PJ.

Aliment Pharmacol Ther

Acupuncture for irritable bowel syndrome: a protocol for a pragmatic randomised controlled trial.

MacPherson H, Bland M, Bloor K, Cox H, Geddes D, Kang'ombe A, Reynolds J, Stamuli E, Stuardi T, Tilbrook H, Torgerson D, Whorwell P.

BMC Gastroenterol

The Manchester Color Wheel: development of a novel way of identifying color choice and its validation in healthy, anxious and depressed individuals.

Carruthers HR, Morris J, Tarrier N, Whorwell PJ.

BMC Med Res Methodol.

Reactivity in health and irritable bowel syndrome.

Carruthers HR, Morris J, Tarrier N, Whorwell PJ.

Aliment Pharmacol Ther

Constipation: a potential cause of pelvic floor damage?

Amselem C, Puigdollers A, Azpiroz F, Sala C, Fernandez-Fraga X, Whorwell PJ, Malagelada JR.

Neurogastroenterol Motil

Lactose and fructose intolerance. In:Pawankar R, Holgate ST, Rosenwasser LJ, editors.

Amir E, Whorwell PJ.

Allergy frontiers: clinical manifestations. Vol 3.

Probiotics: evidence to support their use in irritable bowel syndrome.

Whorwell PJ.

Gastroenterology in Primary Care

Positive diagnosis of irritable bowel syndrome.

Whorwell PJ.

Primary Care Women’s Health Journal

Soluble or insoluble fibre in irritable bowel syndrome in primary care? Randomised placebo controlled trial.

Bijkerk CJ, de Wit NJ, Muris JW, Whorwell PJ, Knottnerus JA, Hoes AW.

BMJ

5-hydroxytryptamine signaling in irritable bowel syndrome with diarrhoea: effects of gender and menstrual status.

Houghton LA, Brown H, Atkinson W, Morris J, Fell C, Whorwell PJ, Lockhart S, Keevil B.

Aliment Pharmacol Ther

Emerging drugs for irritable bowel syndrome.

Shekhar C, Whorwell PJ.

Expert Opin Emerg Drugs

Do probiotics improve symptoms in patients with irritable bowel syndrome?

Whorwell PJ.

Therapeutic Advances in Gastroenterology

The challenge of developing new therapies for irritable bowel syndrome.

Azpiroz F, Whorwell PJ.

Probiotics – Growing evidence to support their use in irritable bowel syndrome.

Whorwell PJ.

Bloating and distension in irritable bowel syndrome: the role of gastrointestinal transit.

Agrawal A, Houghton LA, Reilly B, Morris J, Whorwell PJ.

Hypnotherapy for functional gastrointestinal disorders: a review.

Miller V, Whorwell PJ.

Irritable bowel in the elderly: an overlooked problem.

Agrawal A, Khan MH, Whorwell PJ.

The problem of insoluble fibre in irritable bowel syndrome.

Whorwell PJ.

Behavioural therapy for IBS.

Whorwell PJ.

Using art to help understand the imagery of irritable bowel syndrome and its response to hypnotherapy.

Carruthers HR, Miller V, Morris J, Evans R, Tarrier N, Whorwell PJ.

Evaluation and management of patients with noncardiac chest pain.

Shekhar C, Whorwell PJ.

Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173-010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation.

Agrawal A, Houghton LA, Morris J, Reilly B, Guyonnet D, Goupil Feuillerat N, Schlumberger A, Jakob S, Whorwell PJ.

Tailor treatment to the patient in irritable bowel syndrome.

Shekhar C, Whorwell PJ.

First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor type 3E gene with diarrhea predominant irritable bowel syndrome.

Kapeller J, Houghton LA, Mönnikes H, Walstab J, Möller D, Bönisch H, Burwinkel B, Autschbach F, Funke B, Lasitschka F, Gassler N, Fischer C, Whorwell PJ, Atkinson W, Fell C, Büchner KJ, Schmidtmann M, van der Voort I, Wisser AS, Berg T, Rappold G, Niesler B.

Hum Mol Genet [Epub ahead of print].

Treatment of inflammatory bowel disease: a role for hypnotherapy?

Miller V, Whorwell PJ.

Journal of Clinical and Experimental hypnosis 2008;56:306-317.

Irritable bowel syndrome: an approach to treating patients.

Whorwell PJ.

Digestive Health Matters 2008;17:4-7.

Hypnotherapy for irritable bowel syndrome: the response of colonic and noncolonic symptoms.

Whorwell PJ.

J Psychosom Res 2008; 64 : 621-3.

Bloating and distention in irritable bowel syndrome: the role of visceral sensation.

Agrawal A, Houghton LA, Lea R, Morris J, Reilly B, Whorwell PJ.

Gastroenterology 2008; 134 : 1882-9.

Review article: abdominal bloating and distension in functional gastrointestinal disorders - epidemiology and exploration of possible mechanisms.

Agrawal A, Whorwell PJ.

Aliment Pharmacol Ther 2008; 27 : 2-10.

Dietary aspects of irritable bowel syndrome (IBS).

Whorwell PJ.

Digestive Health Matters 2007;16:6-7.

Tegaserod for the treatment of irritable bowel syndrome and chronic constipation.

Evans BW, Clark WK, Moore DJ, Whorwell PJ.

Cochrane Database Syst Rev 2007;17: CD003960.

Hypnotherapy for non-cardiac chest pain: long-term follow-up.

Miller V, Jones H, Whorwell PJ.

Gut 2007; 56 : 1643.

Effect of the NK(3) receptor antagonist, talnetant, on rectal sensory function and compliance in healthy humans.

Houghton LA, Cremonini F, Camilleri M, Busciglio I, Fell C, Cox V, Alpers DH, Dewit OE, Dukes GE, Gray E, Lea R, Zinsmeister AR, Whorwell PJ.

Neurogastroenterol Motil 2007; 19 : 732-43.

Sigmoid-colonic motility in health and irritable bowel syndrome: a role for 5-hydroxytryptamine.

Houghton LA, Atkinson W, Lockhart S, Fell C, Whorwell PJ, Keevil B.

Neurogastroenterol Motil 2007; 19 : 724-31.

Effect of a second-generation alpha2delta ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome.

Houghton LA, Fell C, Whorwell PJ, Jones I, Sudworth DP, Gale JD.

Gut 2007; 56 : 1218-25.

Guidelines on the irritable bowel syndrome: mechanisms and practical management.

Spiller R, Aziz Q, Creed F, Emmanuel A, Houghton L, Hungin P, Jones R, Kumar D, Rubin G, Trudgill N, Whorwell P.

Gut 2007; 56 : 1770-98.

The growing case for an immunological component to irritable bowel syndrome.

Whorwell PJ.

Clin Exp Allergy 2007;37(6):805-7.

FAQs: irritable bowel syndrome.

Whorwell PJ.

Practitioner 2006;250:29-32.

Treatment of non-cardiac chest pain: a controlled trial of hypnotherapy.

Jones H, Cooper P, Miller V, Brooks N, Whorwell PJ.

Gut 2006;55:1403-8.

Effects of cilomilast, a selective phosphodiesterase 4 inhibitor, on esophageal motility and pH, and orocecal and colonic transit: two single-center, randomized, double-blind, placebo-controlled, two-part crossover studies in healthy volunteers.

Houghton LA, Atkinson W, Whorwell PJ, Morris J, Murdoch RD, Cooper SM, Webber DM, Walls CM.

Clin Ther. 2006;28:569-81.

Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome.

Whorwell PJ, Altringer L, Morel J, Bond Y, Charbonneau D, O'Mahony L, Kiely B, Shanahan F, Quigley EM.

Am J Gastroenterol 2006;101:1581-90.

Bran and irritable bowel syndrome: the primary-care perspective.

Miller V, Lea R, Agrawal A, Whorwell PJ.

Dig Liver Dis 2006;38:737-40.

Relationship of abdominal bloating to distension in irritable bowel syndrome and effect of bowel habit.

Houghton LA, Lea R, Agrawal A, Reilly B, Whorwell PJ.

Gastroenterology 2006;131:1003-10.

Tegaserod in the treatment of constipation predominant functional gastrointestinal disorders.

Agrawal A, Whorwell P.

Therapy 2006;3:475- 484.

Irritable bowel syndrome: diagnosis and management.

Agrawal A, Whorwell PJ.

British Medical Journal 2006;332:280-3.

Mechanisms of diarrhoea in functional gastrointestinal disorders.

Agrawal A, Whorwell PJ.

Corazziari E, editor. Diarrhoeal illness and anal continence control in functional intestinal disorders. Milan: Messaggi International; 2006. pp41-54.

Altered 5-hydroxytryptamine signalling in patients with constipation - and diarrhoea - predominant irritable bowel syndrome.

Atkinson W, Lockhart S, Whorwell PJ, Keeval B, Houghton LA.

Gastroenterology 2006;130:34-43.

Effective management of irritable bowel syndrome - the Manchester model.

Whorwell PJ.

Journal of Clinical and Experimental hypnosis 2006;54:21-26.

Functional bowel disorders: distension and 5 hydroxytryptamine.

Whorwell PJ.

Krause G, Malagelada JR, Preuschoff U.(editors). Functional Disorders of the Gastrointestinal Tract .  Amsterdam; IOS Press; 2005. pp 73-79.

The history of hypnotherapy and its role in irritable bowel syndrome.

Whorwell PJ.

Alimentary Pharmacology and Therapeutics 2005;22: 1061-67.

Barostat testing of rectal sensation and compliance in humans: comparison of results across two centres and overall reproducibility.

Cremonini F, Houghton LA, Camilleri M, Ferber I, Fell C, Cox V, Castillo EJ, Alpers DH, Dewit OE, Gray E, Lea R, Zinsmeister AR, Whorwell PJ.

Neurogastroenterol Motil. 2005;17:810-20.

Hypnotherapy for irritable bowel syndrome: a role in pediatric practice?

Agrawal A, Whorwell PJ.

J Pediatr Gastroenterol Nutr 2005;41:S49-50.

IgG mediated food intolerance in irritable bowel syndrome: real phenomenon or epiphenonemon?

Shanahan F, Whorwell PJ.

American Journal of Gastroenterology 2005;100:1558-9.

Bloating, distension and irritable bowel syndrome.

Lea R, Whorwell PJ.

MedGenMed. 2005;7:18. www.medscape.com/viewarticle/483079.

Towards a better understanding of abdominal bloating and distension in functional gastrointestinal disorders.

Houghton LA, Whorwell PJ.

Neurogastroenterology and Motility 2005;17:500-11.

The role of food intolerance in irritable bowel syndrome.

Lea R, Whorwell PJ.

Gastroenterology Clinics of North America 2005;34:247-55.

Irritable bowel syndrome: unrecognised severity.

Whorwell PJ.

Digestive Health Matters 2005;14:10-11.

Hypnotherapy in the treatment of irritable bowel syndrome.

Gonsalkorale W, Whorwell PJ.

European Journal of Gastroenterology 2005;17:15-20.

Psychological features on the irritable bowel syndrome.

Lea R. Whorwell PJ.

Minerva Medicine 2004;95:443-50.

Management of irritable bowel syndrome with constipation.

Whorwell PJ.

Medscape 2004. Available at: www.medscape.com/viewarticle/477464.

Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial.

Atkinson W, Sheldon T, Shaath N, Whorwell PJ.

Gut 2004;69:254-61.

Irritable bowel syndrome, chronic pelvic inflammatory disease and endometriosis - a comparison of symptomatology.

Lea R, Bancroft, Whorwell PJ.

European Journal of Gastroenterology and Hepatology 2004;16:1269-72.

Diagnostic criteria for IBS: utility and applicability in clinical practice.

Lea R, Hopkins VL, Whorwell PJ.

Digestion 2004;70:210-3.

Inter-digestive and post-prandial antro-pyloro-duodenal motor activities in humans: efftect of 5-hydroxytryptamine 1 receptor agonism.

Calvert EL, Whorwell PJ, Houghton LA.

Aliment Pharmacol Ther 2004;19:805-15.

Technologies in the evaluation of irritable bowel syndrome.

Smout AJ, Azpiroz F, Brummer RJ, Coremans G, Dapoigny M, Muller-Lissner SA, Pcae F, Stockbrugger RM, Vatn M, Whorwell PJ.

Digestion 2004;69:158-65.

Gender and irritable bowel syndrome: the male connection.

Miller V, Whittaker K, Morris JA, Whorwell PJ.

J Clinical Gastroenterology 2004;38:558-60.

Dietary treatment of the irritable bowel syndrome.

Lea R, Whorwell P.

Current treatment options in gastroenterology 2004;7:307-316.

Quality of life and illness costs in irritable bowel syndrome.

Simren M, Brazier J, Coremans G, Dapoigny M, Muller-Lissner SA, Pace F, Smout AJ, Stockbrugger RW, Vatn MH, Whorwell PJ.

Digestion 2004;69:254-61.

Cognitive change in patients undergoing hypnotherapy for irritable bowel syndrome.

Gonsalkorale W, Toner B, Whorwell PJ.

Journal of Psychosomatic Research 2004;56:271-278.

Benefit-risk assessment of Tegaserod in irritable bowel syndrome.

Lea R, Whorwell PJ.

Drug Safety 2004;27:229-42.

Tegasterod for the treatment of irritable bowel syndrome.

Evans BW, Clark W, Moore D, Whorwell PJ.

Cochrane database Syst Rev 2004;1:CD003960.

New insights into the psychosocial aspects of irritable bowel syndrome.

Lea R, Whorwell PJ.

Curr Gastroenterol Rep 2003;5:343-50.

Symptomatic inflammatory bowel disease in remission - it could be irritable bowel syndrome.

Whorwell PJ.

Gastrointestinal Inflammation and Disturbed Gut Function: The Challenge of New Concepts. Falk Symposium. No 130 2003;53-56.

Irritable bowel syndrome or endometriosis, or both?

Lea R, Whorwell PJ.

European Journal of Gastroenterology and Hepatology 2003;15:1131-3.

Role of alimentation in irritable bowel syndrome.

Dapoigny M, Stockbrugger RW, Azpiroz F, Collins S, Coremans G, Muller-Lissner S, Oberndorff A, Pace F, Smout A, Vatn M, Whorwell PJ.

Digestion 2003;67:225-33.

Consensus report: clinical trial guidelines for pharmacological treatment of irritable bowel syndrome.

Corazziari E, Bytzer P, Delvaux M, Holtmann G, Malagelada JR, Morris J,   Muller-Lissner S, Spiller RC, Tack J, Whorwell PJ.

Alimentary Pharmacology and Therapeutics 2003;18:569-80.

Long term benefits of hypnotherapy for irritable bowel syndrome.

Gonsalkorale WM, Miller V, Afzal A, Whorwell PJ.

Gut 2003;52:1623-9.

The prevalence, patterns and impact of irritable bowel syndrome: an international survey of 40,000 subjects.

Hungin AP, Whorwell PJ, Tack J, Mearin F.

Alimentary Pharmacology and Therapeutics 2003;17:643-50.

Increased platelet depleted plasma 5-hydroxytryptamine concentration following meal ingestion in symptomatic female subjects with diarrhoea predominant irritable bowel syndrome.

Houghton LA, Atkinson W, Whitaker RP, Whorwell PJ, Rimmer MJ.

Gut 2003;52:663-70.

Gut focused hypnotherapy normalises disordered rectal sensitivityin patients with irritable bowel syndrome.

Lea R, Houghton LA, Calvert EL, Larder S,Gonsalkorale WM, Whelan V, Randles J, Cooper P,Cruickshanks P, Miller V, Whorwell PJ.

Alimentary Pharmacology and Therapeutics 2003;17:635-42.

Interleukin 10 genotypes in irritable bowel syndrome: evidence for an inflammatory component?

Gonsalkorale WM, Perrey C, Pravica V, Whorwell PJ, Hutchinson IV.

Gut 2003;52:91-3.

Functional Constipation.

Lea R, Whorwell PJ, Kiff E.

Journal of Functional Syndromes 2002;2:86-99.

The rectum: a window on irritable bowel syndrome?

Coremans G, Azpiroz F, Collins S, Dapoigny M, Mull-Lissner SA, Pace F, Smout A, Stockbrugger RW, Whorwell PJ.

Digestion 2002;65:238-49.

A device for 24 hour ambulatory monitoring of abdominal girth using inductive plethysmography.

Reilly BP, Bolton MP, Lewis MJ, Houghton LA, Whorwell PJ.

Physiological Measurement 2002;23:661-70.

Infection and irritability.

Lea R, Whorwell PJ.

Gut 2002;51:305-6.

Serotonergic agents in the treatment of functional gastrointestinal disorders.

Lea R, Whorwell PJ.

Current Treatment Options in Gastroenterology. 2002;5:293-300.

Visceral sensation and emotion: a study using hypnosis.

Houghton LA, Calvert EL, Jackson NA, Cooper P, Whorwell PJ.

Gut 2002;51:701-4.

Long-term improvement in functional dyspepsia using hypnotherapy.

Calvert E, Houghton LA, Cooper P, Morris J, Whorwell PJ.

Gastroenterology 2002;123:1778-85.

Psychotherapy and hypnotherapy in IBS.

Guthrie E, Whorwell PJ.

Camilleri M and Spiller R, editors. Irritable Bowel Syndrome: Diagnosis and Treatment . Chapter 16. London: WB Saunders; 2002. p. 151-159.

The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers.

Houghton LA, Lea R, Jackson N, Whorwell PJ.

Gut 2002;50:471-4.

What do patients with irritable bowel syndrome dream about? A comparison with inflammatory bowel disease.

Lal S, Whorwell PJ.

Digestive and Liver Disease 2002;34:506-9.

Hypnotherapy in irritable bowel syndrome: a large scale audit of a clinical service with examination of factors influencing responsiveness.

Gonsalkorale WM, Cooper P, Cruickshanks PB, Miller V, Randles J, Whelan V, Houghton LA, Whorwell PJ.

American Journal of Gastroenterology 2002;97:954-61.

Irritable bowel syndrome: a drug development minefield.

Whorwell PJ.

Drugs of Today 2001;37:761-5.

Diarrhoea- and constipation- predominant irritable bowel syndrome.

Lea R, Whorwell PJ.

Current Treatment Options in Gastroenterology. 2001;4:299-308.

Abdominal pain.

Whorwell PJ.

Maclean AB, Stones RW, Thornton S, editors . Pain in Obstetrics and Gynaecology. London: RCOG Press; 2001. p. 209-213.

Quality of life in irritable bowel syndrome.

Lea R, Whorwell PJ.

Pharmacoeconomics 2001;19:643-53.

5-HT and the treatment of irritable bowel syndrome - a clinical perspective.

Shaath NM, Whorwell PJ.

Drugs of Today 2001;37:437-40.

Serotonin receptor modulation in irritable bowel syndrome: one step forwards and one step backwards.

Whorwell PJ.

Gut 2001;48:596-7.

Ambulatory abdominal inductance plethysmography: towards the objective assessment of abdominal distension in irritable bowel syndrome.

Lewis MJV, Reilly B, Houghton LA, Whorwell PJ.

Gut 2001;48:216-20.

British Society of Gastroenterology guidelines for the management of the irritable bowel syndrome.

Jones J, Boorman J, Cann P, Forbes A, Gomborone J, Heaton K, Hungin P, Kumar D, Libby G, Spiller R, Read N, Silk D, Whorwell PJ.

Gut 2000;(Suppl II)47:ii1-ii19.

Do male sex hormones protect from irritable bowel syndrome?

Houghton LA, Jackson NA, Whorwell PJ, Morris J.

American Journal of Gastroenterology 2000;95:2296-300.

Functional Dyspepsia and a positive diagnosis of irritable bowel syndrome.

Francis CY, Whorwell PJ.

Heatley RV, editor. Dyspepsia: The Clinical Consequences . Chapter 9. Oxford: Blackwell Science Ltd; 2000. p. 111-28.

Potential pitfalls in the differential diagnosis of irritable bowel syndrome.

Smout A, Azpiroz F, Coremans G, Dapoigny M, Collins S, Muller-Lissner S, Pace F, Stockbrugger RW,Vatn M, Whorwell PJ.

Digestion 2000;61:247-56.

Gynaecological aspects of irritable bowel syndrome.

Whorwell PJ.

Practical Gastroenterology 2000;24:21-4.

Why people with IBS may need to ban the bran.

Whorwell PJ.

Health and Ageing 2000;20-2.

The problem of gas in irritable bowel syndrome.

Whorwell PJ.

American Journal of Gastroenterology 2000;95:1618-9.

Alosetron, a 5HT 3 receptor antagonist, delays colonic transit in patients with irritable bowel syndrome and healthy volunteers.

Houghton LA, Foster JM, Whorwell PJ.

Alimentary Pharmacology and Therapeutics 2000;14:775-82.

Design of treatment trials in functional bowel disorders.

Van Zanten S, Talley NJ, Whorwell PJ.

Drossman DA, Corazziari E, Talley NJ, Thompson WG, Whitehead WE, editors. Rome II - The Functional Gastrointestinal Disorders. Chapter 11. McLean VA: Degnon Associates; 2000.

Nongastrointestinal disorders in the irritable bowel syndrome.

Azpiroz F, Dapoigny M, Pace F, Muller-Lissner S, Coremans G, Whorwell PJ, Stockbrugger RW, Smout A.

Digestion 2000;62:66-72.

Hypnosis for irritable bowel syndrome.

Whorwell PJ.

E Corazziari, editor. Approach to the Patient with a Chronic Gastrointestinal Disorder . Chapter. Milan: Messaggi; 2000. p. 537-44.

5HT 4 receptor antagonism in irritable bowel syndrome: effect of SB-207266-A on rectal sensitivity and small bowel transit.

Houghton LA, Jackson NA, Whorwell PJ, Cooper SM.

Alimentary Pharmacology and Therapeutics 1999;13:1437-44.

New drug profile - tegaserod, a viewpoint.

Whorwell PJ.

Drugs 1999;58:497-8.

Increased prevalence of sicca complex and fibromyalgia in patients with irritable bowel syndrome.

Barton A, Pal B, Whorwell PJ, Marshall D.

American Journal of Gastroenterology 1999;94:1898-901.

Design of treatment trials for functional gastrointestinal disorders.

Veldhuyzen Van Zanten SJ, Talley NJ, Bytzer P, Klein KB, Whorwell PJ, Zinsmeister AR.

Gut 1999;45(suppl II):II69-II77.

Altered oesophageal motility following the administration of the 5HT 1 agonist, sumatriptan.

Foster JM, Houghton LA, Whorwell PJ.

Alimentary Pharmacology and Therapeutics 1999;13:927-36.

Psychosocial background and intervention in the irritable bowel syndrome.

Stockbrugger RW, Coremans G, Creed F, Dapoigny M,Muller-Lissner SA, Pace F, Smouth A, Whorwell PJ.

Digestion 1999;60:175-86.

Physiological and psychological aspects of IBS and the role of hypnosis.

Gonsalkorale W, Houghton LA, Whorwell PJ.

Gastroenterology International 1998;11:36-44.

Bran: may irritate irritable bowel.

Lewis MJV, Whorwell PJ.

Nutrition 1998 ;14:470-1.

Chlamydia trachomatis infection: is it relevant in irritable bowel syndrome?

Francis CY, Prior A, Whorwell PJ.

Digestion 1998;59:157-9.

Efficacy and safety of the peripheral kappa agonist fedotizine versus placebo in the treatment of functional dyspepsia.

Read NW, Abitbol JL, Bardham KD, Whorwell PJ, Fraitag B.

Gut 1997;41:664-8.

Clinical economics review: irritable bowel syndrome.

Wells NEJ, Hahn BA, Whorwell PJ.

Alimentary Pharmacology and Therapeutics 1997;11:1019-30.

Undertaking therapeutic trials in irritable bowel syndrome in the primary care setting.

Whorwell PJ, Coremans G, Dapoigny M, Jones R, Muller-Lissner SA, Muris J, Smouth A, Stockbrugger RW, Pace F.

European Journal of General Practice 1997; 3:149-51.

Getting to grips with constipation.

Whorwell PJ.

Health and Ageing 1997;31-3.

Motility in irritable bowel syndrome.

Muller-Lissner SA, Coremans G, Dapoigny M, Pace F,Smout A, Stockbrugger RW, Tougas G, Whorwell PJ,Wienbeck M.

Digestion 1997;58:196-202.

Neurophysiology and neuropsychiatry of the irritable bowel syndrome.

Dapoigny M, Coremans G, Jule Y, Muller-Lissner SA,Pace F, Smout A, Stockbrugger RW, Whorwell PJ.

Digestion 1997;58:1-9.

Opening the doors of perception in the irritable bowel syndrome.

Houghton LA, Whorwell PJ.

Gut 1997;41:567-8.

Zamifenacin (UK-76,654), a potent gut M 3 selective muscarinic antagonist reduces colonic motor activity in patients with irritable bowel syndrome.

Houghton LA, Rodgers J, Whorwell PJ, Campbell FC, Williams NS, Goka J.

Alimentary Pharmacology and Therapeutics 1997;11:561-8.

The role of fibre in irritable bowel syndrome.

Hammonds R, Whorwell PJ.

Int J Gastroenterology 1997;2:9-12.

High prevalence of irritable bowel syndrome in patients attending urological outpatient departments.

Francis CY, Duffy JN, Whorwell PJ. Morris J.

Digestive Diseases and Sciences 1997;42:404-7.

The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress.

Francis CY, Morris J, Whorwell PJ.

Alimentary Pharmacology and Therapeutics 1997;11:395-402.

Classical diseases revisited: the irritable bowel syndrome.

Francis CY, Whorwell PJ.

Post Graduate Medical Journal 1997;73:1-7.

Selective 5-hydroxytryptamine antagonism: a role in irritable bowel syndrome and functional dyspepsia?

Maxton DG, Morris J, Whorwell PJ.

Alimentary Pharmacology and Therapeutics 1996;10:595-9.

Fibre: not just a load of old bran.

Whorwell PJ.

Cost & Options in the NHS 1996;3:17-8.

Does routine abdominal ultrasound enhance diagnostic accuracy in irritable bowel syndrome?

Francis CY, Duffy JN, Martin DF, Whorwell PJ.

American Journal Gastroenterology 1996;91:1348-50.

Gynaecological aspects of irritable bowel syndrome.

Whorwell PJ.

Participate 1996;4:3-4.

Hypnotherapy and functional bowel disorders.

Gonsalkorale W, Whorwell PJ.

International Journal of Gastroenterology 1996;1:16-9.

Is there effective treatment for irritable bowel syndrome?

Whorwell PJ. Farthing MJG, editor. Clinical Challenges in Gastroenterology. Chapter 13. London: Martin Dunitz; 1996. p179-87.

Symptomatology, quality of life and economic features of irritable bowel syndrome - the effect of hypnotherapy.

Houghton LA, Heyman DJ, Whorwell PJ.

Alimentary Pharmacology and Therapeutics 1996;10:91-5.

IBS - the gender influence.

Whorwell PJ.

Women and IBS. No. 2. Medicom Excel; 1995. p. 2-3.

Therapy of irritable bowel syndrome - an overview.

Pace F, Coremans G, Dapoigny M, Muller-Lissner SA, Smout A, Stockbrugger RW, Whorwell PJ.

Digestion 1995;56:433-42.

Diagnostic procedures in irritable bowel syndrome.

Coremans G, Dapoigny M, Muller-Lissner S, Pace F, Smout A, Stockbrugger RW, Whorwell PJ.

Digestion 1995;56:76-84.

Acute diarrhoea induces rectal sensitivity in women but not men.

Houghton LA, Wych J, Whorwell PJ.

Gut 1995;37:270-4.

Loxiglumide, a CCK-A antagonist in irritable bowel syndrome. A pilot multicentre clinical study.

Cann PA, Rovati LC, Smart HL, Spiller RC, Whorwell PJ.

Annals New York Academy of Sciences 1994;713:449-50.

Bran and irritable bowel syndrome: time for reappraisal.

Francis CY & Whorwell PJ.

Lancet 1994;344:39-40.

Does the menstrual cycle affect anorectal physiology?

Jackson NA, Houghton LA, Whorwell PJ.

Dig Dis Sci 1994;39:2607-11.

Effect of acute stress on anorectal physiology in normal healthy volunteers.

Houghton LA, Prior A, Whorwell PJ.

European J Gastroenterology and Hepatology 1994;6:389-92.

The hypersensitive gut: adequate approach or further confusion?

Stockbrugger RW, Coremans G, Dapoigny M, Muller-Lissner S, Pace F, Smout A, Whorwell PJ.

Digestion 1993;54:331-6.

Cost effective provision of hypnotherapy in a hospital setting: a practical solution.

Taylor EE, Whorwell PJ.

British Journal of Medical Economics 1993;6:75-9.

Physiological effects of emotion: assessment via hypnosis.

Whorwell PJ, Houghton LA, Taylor E, Maxton DG.

Lancet 1992;340:69-72.

Use of medical resources and attitudes to health care of patients with chronic abdominal pain.

Maxton DG, Whorwell PJ.

British Journal of Medical Economics 1992;2:75-9.

Improving clinical trials in irritable bowel syndrome: some practical aspects.

Maxton DG, Morris JA, Whorwell PJ.

European Journal of Gastroenterology & Hepatology 1992;4:337-41.

Outpatients with irritable bowel syndrome: a comparison of first time and chronic attenders.

Guthrie EA, Creed FH, Whorwell PJ, Tomenson B.

Gut 1992;33:361-3.

Abdominal distension in irritable bowel syndrome: the patient's perception.

Maxton DG, Whorwell PJ.

European Journal of Gastroenterology and Hepatology 1992;4:241-3.

Beta-blockade in irritable bowel syndrome - an assessment in anxious patients with diarrhoea.

Maxton DG, Morris J, Whorwell PJ.

Journal of Pharmaceutical Medicine 1991;1:219-23.

A pathophysiological approach to the management of irritable bowel syndrome.

Whorwell PJ.

Summerfield JA, Seymour CA, editors . Horizons in Medicine 3 . Royal College of Physicians; 1991.

Functional bowel symptoms in diabetes: the role of autonomic neuropathy.

Maxton DG, Whorwell PJ.

Post Graduate Medical Journal 1991;67:991-3.

Effect of hyperventilation on distal colonic motility and rectal sensitivityin irritable bowel syndrome.

Maxton DG, Prior A, Whorwell PJ.

Digestion 1991;48:70-4.

More accurate diagnosis of irritable bowel syndrome by the use of ' non-colonic' symptomatology.

Maxton DG, Morris J, Whorwell PJ.

Gut 1991;32:784-6.

Abdominal distension in female patients with irritable bowel syndrome: an exploration of possible mechanisms.

Maxton DG, Martin DF, Whorwell PJ.

Gut 1991;32:662-4.

A double blind study of nicardipine in irritable bowel syndrome.

Prior A, Whorwell PJ.

European Journal of Gastroenterology and Hepatology 1991;3:181-4.

Hypnotic desensitisation of the bowel.

Whorwell PJ.

Read NW, editor. Irritable Bowel Syndrome Oxford: Blackwell Scientific Publications; 1991. p. 122-126.

5 extraintestinal manifestations of irritable bowel syndrome.

Whorwell PJ.

Read NW, editor. Irritable Bowel Syndrome. Oxford Blackwell Scientific Publications; 1991. p. 43-47.

Eating disorders in patients with irritable bowel syndrome: a comparison with inflammatory bowel disease and peptic ulceration.

Guthrie EA, Creed FH, Whorwell PJ.

European Journal of Gastroenterology and Hepatology 1990;2:471-3.

Effect of intra-colonic nicardipine on colonic motility in irritable bowel syndrome.

Maxton DG, Whorwell PJ.

Alimentary Pharmacology & Therapeutics 1990;4:305-8.

Angina like chest pain: head, heart or oesophagus?

Schofield PM, Whorwell PJ.

British Journal of Hospital Medicine 1990;43:443-7.

Changes in rectal sensitivity after hypnotherapy in patients with irritable bowel syndrome.

Prior A, Colgan SM, Whorwell PJ.

Gut 1990;31:896-8.

Anorectal manometry in irritable bowel syndrome: differences between diarrhoea and constipation predominant subjects.

Prior A Maxton DG Whorwell PJ.

Gut 1990;31:458-62.

Irritable bowel syndrome in the gynaecological clinic: a survey of 798 new referrals.

Prior A, Wilson K, Whorwell PJ, Faragher EB.

Digestive Diseases and Sciences 1989;34:1820-4.

Diagnosis and management of irritable bowel syndrome.

Whorwell PJ.

Journal Royal Society of Medicine 1989;82:613-4.

Ranking of symptoms by patients with irritable bowel syndrome.

Maxton DG, Morris JA, Whorwell PJ.

British Medical Journal 1989;299:1138-9.

Gynaecological consultations in patients with the irritable bowel syndrome.

Prior A, Whorwell PJ.

Gut 1989;30:996-8.

Oesophageal function in patients with angina pectoris: a comparison of patients with normal coronary angiograms and patients with coronary artery disease.

Schofield PM, Whorwell PJ, Brooks NH, Bennett DH, Jones PE.

Digestion 1989;42:70-8.

A double blind trial of an alpha-2 agonist in the treatment of irritable bowel syndrome.

Prior A, Wilson KM, Whorwell PJ.

Alimentary Pharmacology and Therapeutics 1988;2:535-9.

Angina like chest pain: a joint medical and psychiatric investigation.

Colgan SM, Schofield PM, Whorwell PJ, Bennett DH, Brooks NH, Jones PE.

Post Graduate Medical Journal 1988;64:743-6.

Differentiation of "oesophageal" and "cardiac" chest pain.

Schofield PM, Whorwell PJ, Jones PE, Brooks NH, Bennett DH.

American Journal of Cardiology 1988;62:315-6.

Controlled trial of hypnotherapy in relapse prevention of duodenal ulceration.

Colgan SM, Faragher EB, Whorwell PJ.

Lancet 1988;331:1299-300.

Effect of nicardipine on gastric acid secretion in man.

Prior A, Whorwell PJ.

Alimentary Pharmacology and Therapeutics 1987;1:643-7.

Severe sexual dysfunction in women with the irritable syndrome: a comparison with inflammatory bowel disease and duodenal ulceration.

Guthrie E, Creed FH, Whorwell PJ.

British Medical Journal 1987;295:577-8.

Exertional gastro-oesophageal reflux: a mechanism for symptoms in patients with angina pectoris and normal coronary angiograms.

Schofield PM, Bennett DH, Whorwell PJ, Brooks NH, Bray CL, Ward C, Jones PE.

British Medical Journal 1987;294:1459-61.

The irritable bowel syndrome.

Whorwell PJ.

Advanced Medicine 23. London: Balliere & Tindall; 1987. p.132-6.

Left ventricular function and oesophageal function in patients with angina pectoris and normal coronary angiograms.

Schofield PM, Brooks NH, Colgan SM, Bennett DG, Whorwell PJ, Bray CL, Ward C, Jones PE.

British Heart Journal 1987;58:218-24.

Reduction of colonic motility by intravenous nicardipine in irritable bowel syndrome.

Prior A, Harris SR, Whorwell PJ.

Gut 1987;28:1609-12.

Therapeutic options in irritable bowel syndrome: a review of patients attending a gastroenterology clinic.

Langdon SJ, Jackson CW, Whorwell PJ.

British Journal of Pharmaceutical Practice 1987;9:62-4.

Double blind study of ispaghula in irritable bowel syndrome.

Prior A, Whorwell PJ.

Gut 1987;28:1510-3.

Exclusion diets in irritable bowel syndrome: are they worthwhile?

McKee AM, Prior A, Whorwell PJ.

Journal of Clinical Gastroenterology 1987;9:526-8.

Hypnotherapy in severe irritable bowel syndrome: further experience

Whorwell PJ, Prior A, Colgan SM.

Gut 1987;28:423-5.

Bladder smooth muscle dysfunction in patients with irritable bowel syndrome.

Whorwell PJ, Lupton EW, Erduran D, Wilson K.

Gut 1986;27:1014-7.

Non-colonic features of irritable bowel syndrome.

Whorwell PJ, McCallum M, Creed FH, Roberts CT.

Gut 1986;27:37-40.

Controlled trial of hypnotherapy in the treatment of severe refractory irritable bowel syndrome.

Whorwell PJ, Prior A, Faragher EB.

Lancet 1984;324:1232-4.

Symptoms of irritable bowel syndrome in ulcerative colitis in remission.

Isgar B, Harmen M, Kaye MD & Whorwell PJ.

Gut 1983;24:190-2.